L-Theanine, also known as L-gamma-glutamine and N-propyl glutamine, is the amino acid analogues of the proteogenic amino acids L-glutamate and L-glutamine and is found primarily in specific plant and fungal species. L-theanine, an amino acid found in green tea leaves, has been shown to promote relaxation and alertness. It combines alert relaxation with calm concentration, an ingredient favored by those seeking to optimize cognitive function and reduce stress.
At present, the mechanism of L-theanine has been relatively clear:
① Glucolipid metabolism is regulated by insulin and AMPK (AMP active protein kinase) and their downstream signaling pathways;
② By competing with glutamate receptors to inhibit the neurotoxicity caused by increased glutamate concentration, neuroprotective effect;
③ Improve sleep and regulate mood by increasing α -brainwave and decreasing β -brainwave;
④ Inhibit the growth and metastasis of tumor cells by down-regulating the ratio of Bcl-2/Bax protein (apoptosis suppressor gene/apoptosis promoter gene);
(5) Caspase-3 protein can protect normal cells by antioxidation and inhibiting apoptosis.
Post time: May-30-2022
